Are we Aspir-in or Aspirin-out for DVT Prophylaxis in Orthopedic Patients

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Monday, June 8, 2026, 7:00 AM - Thursday, June 8, 2028, 11:59 PM


AMA PRA Category 1 Credits™ (0.75 hours), ACPE Contact Hour(s) (0.75 hours), ANCC Contact Hour(s) (0.75 hours), General Attendance (0.75 hours), IPCE Credit(s) (0.75 hours), Non-Physician Attendance (0.75 hours)

There is ongoing uncertainty about the role of aspirin in VTE prophylaxis after orthopedic surgery. While evidence shows aspirin can reduce clot risk compared to placebo and may be noninferior to anticoagulants in certain lower-risk settings, other trials suggest anticoagulants are more effective, particularly in higher-risk arthroplasty patients. Variability in study design, patient populations, dosing, and duration of therapy makes it difficult to draw firm conclusions, and current guidelines reflect this by offering only conditional, low-certainty recommendations. Overall, the main gap is determining which patients are best suited for aspirin versus stronger anticoagulation, underscoring the need for more consistent, high-quality research to guide practice.

1. Discuss the pathophysiology and risk of VTE in orthopedic surgery
2. Review major clinical practice guidelines for VTE prophylaxis
3. Identify best practices for VTE prevention in patients undergoing orthopedic fracture and/or repair

This activity was planned by and for the healthcare team, and learners will receive 0.75 IPCE credits for learning and change.

Cancellation Policy

Cancellations received in writing no less than 20 days before the course will be refunded, less a 20% administrative fee. No refunds will be made on cancellations received after that date. Please send cancellation requests to [email protected]

Ascension reserves the right to cancel or postpone this program if necessary; in the event of cancellation, course fees will be fully refunded. We are not responsible for other costs incurred such as non-refundable airline tickets or hotel penalties.

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Ascension adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.